Bcl-6 Oncoprotein蛋白抗體
Clone LN22
7 mL BOND ready-to-use PA0204 P (HIER)
Antigen Background
Bcl-6 is a proto-oncogene that encodes a Kruppel-type zinc-finger protein of
95 kD and shares homology with other transcription factors. Bcl-6 protein is
mainly expressed in normal germinal center B cells and related lymphomas.
It has been shown that the Bcl-6 proto-oncogene is involved in chromosome
rearrangements at 3q27 in non-Hodgkin's lymphomas and Bcl-6 rearrangements have also been detected in 33 to 45 percent of diffuse large B cell
lymphomas. Immunohistochemistry has been reported to show the Bcl-6
gene product to be detectable in follicular lymphomas, diffuse large B cell
lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant
Hodgkin's disease.
Also available as a liquid concentrate, refer to page 99
Human diffuse large B cell lymphoma: immunohistochemical staining for Bcl-6 using PA0204.
Note nuclear staining of neoplastic cells. Paraffin section.
更新時(shí)間:2024/11/12 13:40:42
經(jīng)營(yíng)許可證號(hào):滬寶食藥監(jiān)械經(jīng)營(yíng)許20220040號(hào)
標(biāo)簽:Bcl-6 蛋白抗體 Bcl-6 Oncoprotein